Atypical endometrial hyperplasia should be highly valued, as about 1/3 of atypical hyperplasia will develop into endometrial cancer. Treatments of this disease mainly include drug therapy and surgery.
Drug therapy: suitable for women who are under age 40 and have fertility requirements
1. Western medicine treatment: progestational hormone
Progestational hormone is always used in western medicine treatment. Patients with mild symptoms can choose small dose of progesterone for half cycle. In more severe cases, patients always receive continuous treatment of large-dose progestogen.
The dosage and administration of pregnancy hormone drugs:
Caproic acid progesterone: the usual dose is 250-500mg by intramuscular injection two or three times a week.
Megestrol acetate: the suggest dose is 40 to 160mg given as a simple daily dose.Medroxyprogesterone: the dose recommended is 10 to 30mg daily in 2-3 divided doses orally.
This kind of therapy is with canceration risk, and the recurrence rate is high, so clinically, it is poorly accepted.
2. Traditional Chinese medicine treatment: Fuyan Pill
In the formula of Fuyan Pill, scutellaria baicalensis has heat-clearing, antidotal and hemostatic efficacy; gardenia is hemostatic and detumescent; peach kernel can promote blood circulation and resolve blood stasis; licorice is able to tonify the spleen, eliminate toxic materials, etc.
The above herbs are reasonably combined in certain proportion, thus created the medicine, Fuyan Pill, which can eradicate the atypical endometrial hyperplasia. It can eliminate symptoms and enhance immunity at the same time, hence restoring the normal physiological function of the uterus. Consequently, it radically cures the endometrial hyperplasia and effectively prevents the disease relapse.
Surgery: suitable for women who have no fertility requirements, especially the menopausal women
The main method of surgeries is total hysterectomy which rules out endometrial cancer. Hysterectomy has curative effect in radically curing the disease. But it brings more traumas, and affects the pelvic structure and ovarian blood supply. As a result, total hysterectomy may affect the patients' life quality after surgery.
In addition, if the patients require reserving the uterus, or they cannot bear the surgery due to physical conditions, they can choose minimally invasive treatment to remove lesions.
All in all, atypical endometrial hyperplasia cannot be neglected. And the treatment should be selected according to a comprehensive consideration such as the patients'age, fertility requirements, degree of disease, general health, and so on.
