When endometrial hyperplasia occurs, a biopsy of pathological tissue is needed for symptoms can recur after routine treatments like progestin therapy and ovulation induction treatment. Besides common simple endometrial hyperplasia and complex endometrial hyperplasia, there is a type of hyperplasia which is hardly to be seen, that is atypical endometrial hyperplasia, it is a type of precancerous lesions with a rate of almost 30 percent to be developed into endometrial cancer. So an active treatment is needed.
The first choice of getting atypical endometrial hyperplasia is a surgery.
Patients with endometrial hyperplasia have very big possibility to get a cancer if they were diagnosed with atypical endometrial hyperplasia after curettage, so atypical endometrial hyperplasia is called precancerous lesions. A surgery is the first choice for such a high rate of precancerous lesions, the main surgery is panhysterectomy to remove the whole uterus. In order to prevent the transfer of malignant transformation, it is necessary to cut both ovaries if endometrial cancer is diagnosed in frozen section pathological examination, or the cancer is confirmed by pathological examination after a surgery.
Conservative treatment is a priority for patients with atypical endometrial hyperplasia who want to give birth in the future.
Most patients of atypical endometrial hyperplasia got married before and gave birth already, so they don’t have strong demand for giving birth again, in order to prevent transfer of malignant transformation, the best treatment is a hysterectomy or together with ovaries on both sides. But for young patients who have strong demand for giving birth, they can try conservative treatments of endometrial hyperplasia for 3-6 months first. megestrol acetate 160g daily can be used in a big dose, keep doing this for 3 months, then have a check and do biopsy of tissues.
If results of two endometrial reexaminations are good, or even pathological biopsy is not atypical hyperplasia, it means there is a good reversion of endometrium. If the result of pathological biopsy is not good enough, patients can postpone the treatment to 12 months and strengthed the treatment during this period of time, take megestrol acetate 320mg daily. If precancerous lesions still exists after the reexaminations, then surgeries are necessary for patients, they can’t still take giving birth into consideration but receive surgeries immediately.
There is one thing needs to be paid attention, that is megestrol acetate is a big dose of progestational hormone treatment which can do harm to liver, kidney and may cause overweight, thrombus, abnormal hyperplasia of breast etc. So during the treatment of megestrol acetate, besides reexamine the condition of endometrium regularly, a patient needs to do checks of liver function, kidney function and breast ultrasound also, and if there is something abnormal, a timely treatment can be a good choice.
While herbal medicine Fuyan Pill is provided with good effects on curing female disease of endometrial hyperplasia. It can reduce the symptoms effectively, and won't cause any side effects, naturally and safelly.
Warm reminded: Even endometrial hyperplasia is an abnormal hyperplasia in endometrium, it has some relationship to endocrine disruptor and ovarian dysfunction to some extent, so preventions are needed even after endometrial hyperplasia’s being cured to avoid another hyperplastic change of the gland of endometrial tissues.
